We are a group of scientists at the Cavendish Lab, University of Cambridge, UK. Our research is focused on understanding transport processes through membranes for biosensing applications.
Since the pandemic we are mainly interested in understanding RNA, its structure and its relation to biology and disease. More details on our current and past research interests can be found here. Since the start, the lab aims to achieve a maximum level of control over all parameters in our experiments. Our main technique remains resistive-pulse sensing with nanopores especially in combination with DNA and now RNA nanotechnology
Our interdisciplinary team combines researchers with expertise in physics, engineering, physical chemistry, biochemistry/biology, and micro- and nanofabrication.
In case you are interested in working with us, please get in touch with Ulrich by email: ufk20 (at) cam.ac.uk.
We gratefully acknowledge funding of our work from various sources including:
15/10/2023 Michealmas Update.
We welcome Michaelmas term and Siong Chen, who started his MPhil on RNA analysis with nanopores.
We also welcome two visiting PhD students, Sara de Braganca from the Moreno Lab in Madrid and Kevin Neis from the Kjems Lab at Aarhus.
Ran Tivony started his own lab now at Ben-Gurion University. We wish him all the best for his start in these challenging times.
In collaboration with the lab of Gideon Coster we investigated the influence of DNA structures on DNA replication. The paper was published in The Embo Journal.
7/8/2023 dCas9 screened with nanopores.
26/7/2023 DNA signals depend on everything.
5/7/2023 DNAo nanocavities.
3/7/2023 July 2023 update.
The Radenovic and Fantner labs at EPFL characterised our DNA carrier systems with controlled nanopipette translocation. Read the full story in Nature Nanotechnology now. Otherwise we are getting ready for the summer conference and workshop season. Yunxuan attended the Faraday discussion on Ionotronics in June. Frank and Ulrich will be in Lyon for the Nanofluidics in Physics and Biology organised by Fabien Montel.